Santa Ana Obesity And Type 2 Diabetes Clinical Trial



Santa Ana Obesity And Type 2 Diabetes Clinical Trial

Obesity And Type 2 Diabetes Clinical Trial

Obesity And Type 2 Diabetes Clinical Trial

The accumulation of excessive body fat can contribute to the development of type 2 diabetes. There is a direct correlation between an increase in body mass index (BMI) and the development of type 2 diabetes. Type 2 diabetes is a condition where the body is resistant to insulin and retains high blood sugar levels. Millions of people in the U.S. suffer from obesity and type 2 diabetes. Diabetes is associated with other complications like kidney disease, heart disease, vision loss, and nerve damage. As of 2023, the adult obesity in the United States was 20%, with an average prevalence of 29% in the Western states.

Across the United States, around 38.4 million adults have diabetes, both diagnosed and the undiagnosed cases. The sad part is that most people do not even know that they have diabetes. According to the CDC, 1 in 4 people with diabetes…

Obesity And Type 2 Diabetes Prevalence

As outlined by the OC Healthcare Agency, 24.2% of people in Orange County are obese. According to Data Commons, the percentage of obese adults is close to 30%. Across California, around 3.6 million adults, which is around 11.7% of the population, live with undiagnosed diabetes according to the American Diabetes Association.

Obesity And Type 2 Diabetes Clinical Trial Santa Ana

Our obesity and type 2 diabetes clinical trial Santa Ana monitors an investigational injectable therapy administered once a week. The treatment seeks to help people with obesity and type 2 diabetes mellitus to lower body weight and lower A1C. The treatment is performed under the careful supervision of a medical professional.

Here is what to expect from the clinical trial:

  • The clinical trial focuses on people with obesity and type 2 diabetes mellitus
  • It involves an investigational therapy whereby a subcutaneous injectable is administered weekly
  • The clinical trial is randomized, placebo-controlled, and double-blind
  • The main objective of the study is to check the changes in body weight and HbA1C
  • The secondary objectives of the study include weight loss, reduction in HbA1c, changes in blood pressure, waist circumference, and lipid levels.
  • The study duration ranges from 56 to 72 weeks. During the trial, the participants’ treatment, dose titration, screening, and follow-up
  • The clinical trial is located at Paragon Rx Clinical in Santa Ana, CA.
  • We have a bilingual team with featured languages including English, Chinese, Vietnamese, and Spanish.
  • Participants may be reimbursed for their time and travel costs incurred while participating in the study.
  • The participants incur no cost for all protocol-related evaluations and the study medication.
  • Unlike what some people assume, the clinical trial is not a research
  • The participants can receive a placebo or the investigational medication, and the participants do not know whether they are receiving medication or a placebo
  • The participation in the clinical trial is voluntary, and the trial can only commence after a participant consents

The Science Behind The Injectable

Incretin-based therapies play an important role in weight management and blood sugar level control. Weekly incretin-based treatments lead to significant weight loss when used alongside other lifestyle measures and also improve HbA1C. The clinical trial is investigational, and we do not rely on a specific brand. The researchers just focus on studying once-a-week incretin-based treatments for obesity and type 2 diabetes. They also focus on the outcomes that the therapy can influence.

What To Expect

Here is what to expect upon consenting to the clinical trial:

The pre-screening call lasts between 10 and 15 minutes. The research coordinator can pose several questions to find out if the applicant qualifies to participate in the clinical trial. If the potential participant is deemed suitable, we will schedule an in-person screening.

Eligible participants are assigned randomly to either the placebo or the investigational injectable. The participants receive the medication on self-injection using a tiny subcutaneous needle. There will also be a dose-titration plan in place.

At the in-person screening, we will obtain informed consent from the participant. We will review your medical history, ECG, vital signs, and blood work. We will also perform a pregnancy test in women. Additionally, our experts will review your current lifestyle and any medications you may be taking.

Participants will make regular visits, typically every two to four weeks. During these visits, we will measure their waist circumference, take their vital signs, and record their weight. We will also perform lab tests, including HbA1 at set intervals. Throughout the clinical trial, we check the participants for tolerability to the treatment and any adverse side effects. Our experts also offer lifestyle counseling in line with the clinical study protocol.

Upon completing the clinical trial, we will conduct a final assessment and guide you through the next steps.

The Potential Advantages Of Participating in an Obesity And Diabetes Type 2 Clinical Trial Santa Ana

The Potential Advantages Of Participating in an Obesity And Diabetes Type 2 Clinical Trial Santa Ana

The potential advantages of participating in the clinical trial include the following:

  • Close medical monitoring for the participants throughout the clinical trial at no cost
  • The time commitment is limited since the visits are brief
  • Possible improvements in weight, cardio metabolic markers, and HbA1c
  • Access to advanced research that improves the standard of care
  • Where applicable, participants are compensated for time and travel

Risks and Side Effects

All clinical trials have potential risks. Some of the possible side effects of the trial include nausea, diarrhea, vomiting, abdominal discomfort, constipation, and potential reaction at the injection site. Before you participate in the study, your study physician will review your medical history and explain all the possible risks and side effects.

Eligibility for Obesity And Type 2 Diabetes Clinical Trial Santa Ana

The final qualification is determined after screening by the physician investigator, and it depends on the study study protocol. The general criteria for eligibility include:

  • The participants should be between 18 and 75 years old
  • The participant should have been diagnosed with type 2 diabetes mellitus, and the diagnosis should have been made more than 6 years ago
  • At screening, the A1C should range from 7.0% to 10.5% but the range could vary depending on the clinical study protocol

Exclusions From Obesity And Type 2 Diabetes Clinical Trial Santa Ana

People who can be excluded from participating in the obesity and type 2 diabetes clinical trial Santa Ana include:

  • People with serious gallbladder disease or pancreatitis
  • People with type 1 diabetes
  • Pregnant or breastfeeding women
  • A recent cardiac arrest event
  • Uncontrolled hypertension
  • If the participant has used other investigational products in the last 30 days

Safety Precautions During Study

Here are some safety measures to consider:

  • Avoid participating in the study when pregnant or stop participating in the clinical trial if you are trying to get pregnant
  • Regular lab tests and safety checks
  • If you feel uncomfortable at any point in the study, you can withdraw
  • Contact the study coordinator in case of any concerns

Find Reliable Obesity And Type 2 Diabetes Clinical Trial Santa Ana

Participating in our obesity and type 2 diabetes clinical Santa Ana can offer many benefits, including the elimination of obesity and type 2 diabetes. At Paragon Rx Clinical, we offer participation in clinical trials at no cost to participants. We administer investigational medication while closely observing the participants. Participants must give consent before participating in the clinical trial. The study is randomized, and while some participants received investigational medication, others received a placebo. In addition to offering the clinical trial at no cost, we also compensate participants for their time and travel expenses in approved cases. If you or a loved one would like to participate in the clinical trial, please contact us at 714-539-3013.

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