Anaheim Obesity & Type 2 Diabetes Clinical Trial



Anaheim Obesity & Type 2 Diabetes Clinical Trial

Obesity & Type 2 Diabetes Clinical Trial

Obesity & Type 2 Diabetes Clinical Trial

Type 2 diabetes mellitus (T2DM) and obesity are two of the most prevalent medical conditions in the world and are closely interconnected. Generally, obesity occurs when a person has excessive, unhealthy body fat. This unhealthy body fat heightens the body’s resistance to insulin. Over time, this could lead to T2DM, a health condition that causes the body to be unable to regulate blood sugar levels properly.

Since these two conditions often occur together, and one worsens the other, clinical researchers conduct trials to test new ways of treating or managing them. At Paragon RX Clinical, we have not been left behind. We are conducting an obesity & type 2 diabetes

The Link Between T2DM and Obesity

Obesity contributes to T2DM through various biological mechanisms. Excessive fat tissue, particularly around the belly, interferes with the cells’ response to insulin. Insulin is a hormone that regulates the body’s blood sugar. It moves the glucose from the blood into the body cells. When these cells reach a point and start resisting insulin, the sugar in the blood fails to decrease, making the pancreas work harder. Eventually, the pancreas may fail to function correctly, leading to the development of T2DM.

Currently, the treatment options for obesity are medication, lifestyle changes, and even surgery. For T2DM, physicians generally recommend exercise, dietary changes, blood-sugar-lowering drugs, and, in advanced stages, insulin therapy. Although there are many treatments for T2DM, our obesity & type 2 diabetes clinical trial in Anaheim continues to study safer, better, and more efficient ways of assisting people in managing the two conditions simultaneously.

What Are Clinical Trials?

Generally, clinical trials are research studies that test a medication, medical treatment, lifestyle intervention, or device on participants who have volunteered to participate in the study. These trials aim to establish whether the above are effective and safe. Most trials have multiple phases. These are

  • Phase 1 tests the safety of a medication, medical treatment, lifestyle intervention, or device on a smaller group.
  • Phase 2 tests the effectiveness of the mentioned approaches, continuing to monitor their safety.
  • Phase 3 tests compare the new approaches to standard care in a large population.
  • Phase 4 is done after approval. The purpose is to track any long-lasting effects.

Strict ethical regulations govern clinical trials. These include

  • Confidentiality
  • Informed consent
  • Close monitoring of side effects.

For the obesity and type 2 diabetes trial, participants may include adults with T2DM, obesity, or both, depending on the study goals.

Expectations Upon Joining

This is what you can expect when you join our obesity & type 2 diabetes clinical trial in Anaheim:

You will receive a prescreening call from our research coordinator, which will last approximately ten to fifteen minutes. They will ask you some confidential questions for the purpose of eligibility assessment. If appropriate, they will set up a face-to-face screening visit

You will undergo a final assessment and be guided on what to do next. Most of these visits are short. Some include ECG or fasting labs.

During this visit, the research coordinator will explain the concept of informed consent. After which, they will obtain your medical history, vital signs, and ECG. They will also conduct blood work tests, including fasting labs and an HbA1c test. You will also undergo pregnancy testing if applicable. After that, the research coordinator will review your current lifestyle and medication.

  • These visits will occur every two to four weeks. During these visits, the research coordinator will:
  • Check your vitals, waist circumference, and weight
  • Check your HbA1c at specific intervals.
  • Conduct check-ins for side effects and tolerability
  • Refill study medication
  • Conduct lifestyle counseling per the protocol

If you qualify for the trial, you will be randomly assigned to receive the placebo or the investigational injectable. You will undergo training on how to inject yourself and be given a dose titration plan.

Possible Benefits of Participating in the Clinical Trial

Participating in this clinical trial comes with several benefits, including:

  • Close free medical monitoring from the beginning to the end of the study
  • Access to state-of-the-art research that might shape future standards of medical care
  • Possible improvement in HbA1c, cardiometabolic markers, and weight.
  • Compensation for travel and time where allowed
  • Contribution to medicine that might assist your community, particularly in areas burdened with diabetes and obesity

Possible Side Effects, Risks, and Safeguards

Every clinical research study has risks. Prevalent side effects that arise after using once-weekly incretin-pathway injectables are

  • Vomiting
  • Nausea
  • Constipation
  • Diarrhea
  • Abdominal discomfort
  • Reactions at the injection site

Overview of Our Obesity Type 2 Diabetes Clinical Trial In Anaheim

Our Anaheim clinical trial is on obesity with T2DM, and the investigational therapy is a once-weekly injectable. The primary objective of this trial is to track changes in HbA1c and body weight. The secondary objectives include: 

  • Proportion achievement of more than or equal to 5 percent or more than or equal to 10 percent weight loss
  • Changes in lipids, waist circumference, and blood pressure 
  • Proportion of achievement of HbA1c of less than 7 percent

Our obesity & type 2 diabetes clinical trial in Anaheim is only investigational. It does not utilize an approved brand. That said, participants might receive a placebo or the investigational medicine. The research study is free of charge to all participants. Participation is voluntary and commences only after the informed consent process has been completed. 

Who Can Qualify for Our Obesity & Type 2 Diabetes Clinical Trial in Anaheim?

Various groups of people may qualify for our obesity & type 2 clinical trial in Anaheim. However, our physician investigator and study protocol determine final eligibility after screening. The general criteria for eligibility are as follows: 

  • Age: You must generally be between 18 and 75 years.
  • Diagnosis: You must have been diagnosed with T2DM. Usually, you must have had it for more than six months. 
  • Stable background therapy: You must have had stable metformin doses or doses of other non-insulin agent for several weeks pre-screening 
  • Body mass index (BMI): Your BMI should be more than 30 kg per square meter or more than 27 kg per square meter with no less than one weight-related comorbidity, like type 2 diabetes mellitus. 

Find a Reliable Obesity and Type 2 Diabetes Clinical Research Center Near Me

Do you wish to participate in an obesity & type 2 diabetes clinical trial in Anaheim? We at Paragon RX Clinical can make that happen. Participating in a clinical trial can provide you with access to brand-new treatments and enable you to receive expert medical attention. You need not worry about your data, as it is handled confidentially in accordance with the study protocol and HIPAA guidelines. We also offer flexible scheduling, free parking, and bilingual staff. Call us at 714-539-3013 for more information.

10+

Years in Clinical Research

100%

Multilingual Staff

6

Days/Week

To fit your busy Schedule

Participate in a Clinical Trial Today

Discover How You Can Help Advance Medicine for a Better Tomorrow

Read More